GPKOW Gene Summary [Human]
This gene encodes a putative RNA-binding protein containing G-patch and KOW (Kyprides, Ouzounis, Woese) domains. The encoded protein interacts directly with protein kinase A and protein kinase X and is also found associated with the spliceosome. [provided by RefSeq, Aug 2013]
Details
| Type | Protein Coding |
| Official Symbol | GPKOW |
| Official Name | G-patch domain and KOW motifs [Source:HGNC Symbol;Acc:HGNC:30677] |
| Ensembl ID | ENSG00000068394 |
| Bio databases IDs | |
| Aliases | G-patch domain and KOW motifs, G patch domain containing 5 |
| Synonyms | 4432411B18, DXErtd697e, DXImx41e, GPATC5, GPATCH5, G-patch domain and KOW motifs, LOC682436, Mos2, SPP2, T54 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human GPKOW often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- G-patch domain
- 6-pyruvoyl-tetrahydropterin synthase related domain (membrane protein)
- protein binding
- RNA binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- spliceosomes
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human GPKOW gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- nuclear mRNA splicing, via spliceosome
Cellular Component
Where in the cell the gene product is active
- nucleus
- spliceosomal complex
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- RNA binding
- protein binding