Gpkow Gene Summary [Rat]
Predicted to enable RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in nucleoplasm. Predicted to be part of spliceosomal complex. Orthologous to human GPKOW (G-patch domain and KOW motifs). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Gpkow |
| Official Name | G patch domain and KOW motifs [Source:RGD Symbol;Acc:1583600] |
| Ensembl ID | ENSRNOG00000022939 |
| Bio databases IDs | |
| Aliases | G patch domain and KOW motifs |
| Synonyms | 4432411B18, DXErtd697e, DXImx41e, GPATC5, GPATCH5, G-patch domain and KOW motifs, LOC682436, Mos2, SPP2, T54 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Gpkow often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- G-patch domain
- 6-pyruvoyl-tetrahydropterin synthase related domain (membrane protein)
- protein binding
- RNA binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- spliceosomes
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Gpkow gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- nuclear mRNA splicing, via spliceosome
Cellular Component
Where in the cell the gene product is active
- nucleus
- spliceosomal complex
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- RNA binding
- protein binding