DDX43 Gene Summary [Human]
The protein encoded by this gene is an ATP-dependent RNA helicase in the DEAD-box family and displays tumor-specific expression. [provided by RefSeq, Jul 2008]
Details
| Type | Protein Coding |
| Official Symbol | DDX43 |
| Official Name | DEAD-box helicase 43 [Source:HGNC Symbol;Acc:HGNC:18677] |
| Ensembl ID | ENSG00000080007 |
| Bio databases IDs | |
| Aliases | DEAD-box helicase 43, cancer/testis antigen 13 |
| Synonyms | CT13, DEAD-box helicase 43, HAGE |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human DDX43 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- KH-like RNA-binding domain
- DEAD/DEAH box helicase
- helicase superfamily c-terminal domain
- K homology RNA-binding domain
- protein binding
- Helicase conserved C-terminal domain
- RNA helicase
- RNA binding
- KH domain
- K homology (KH) RNA-binding domain, type I
- Type III restriction enzyme, res subunit
- N-terminal helicase domain of the DEAD-box helicase superfamily
- DEAD-like helicases superfamily
- P-loop containing Nucleoside Triphosphate Hydrolases
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human DDX43 gene, providing context for its role in the cell.
Molecular Function
What the gene product does at the molecular level
- ATPase activity
- ATP binding
- protein binding
- RNA binding
- RNA helicase activity
- mRNA binding