CPXM1 Gene Summary [Human]
This gene likely encodes a member of the carboxypeptidase family of proteins. Cloning of a comparable locus in mouse indicates that the encoded protein contains a discoidin domain and a carboxypeptidase domain, but the protein appears to lack residues necessary for carboxypeptidase activity.[provided by RefSeq, May 2010]
Details
| Type | Protein Coding |
| Official Symbol | CPXM1 |
| Official Name | carboxypeptidase X, M14 family member 1 [Source:HGNC Symbol;Acc:HGNC:15771] |
| Ensembl ID | ENSG00000088882 |
| Bio databases IDs | |
| Aliases | carboxypeptidase X, M14 family member 1, carboxypeptidase-like protein X1 |
| Synonyms | carboxypeptidase X (M14 family), member 1, carboxypeptidase X, M14 family member 1, CPX1, CPXM |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human CPXM1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Zinc carboxypeptidase
- Zn_pept domain
- Coagulation factor 5/8 C-terminal domain, discoidin domain
- peptidase
- F5/8 type C domain
- Peptidase_M14NE-CP-C_like
- M14 family of metallocarboxypeptidases and related proteins
- CarboxypepD_reg-like domain
- Carboxypeptidase regulatory-like domain
- FA58C
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
- MAPK3
- Spag6l
disease
- kidney disease
- obesity
- hypertrophic scarring
- urothelial bladder carcinoma
- transitional cell bladder cancer
- keratocystic odontogenic tumor
- keratocystic odontogenic tumors
- Wilms tumor
- Wilms tumorigenesis
role in cell
- expression in
- differentiation
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human CPXM1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- proteolysis
Cellular Component
Where in the cell the gene product is active
- extracellular space
Molecular Function
What the gene product does at the molecular level
- zinc ion binding
- metallocarboxypeptidase activity