SLC5A4 Gene Summary [Human]
Predicted to enable glucose:sodium symporter activity and proton transmembrane transporter activity. Predicted to be involved in sodium ion transport. Predicted to act upstream of or within proton transmembrane transport. Predicted to be active in plasma membrane. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | SLC5A4 |
| Official Name | solute carrier family 5 member 4 [Source:HGNC Symbol;Acc:HGNC:11039] |
| Ensembl ID | ENSG00000100191 |
| Bio databases IDs | |
| Aliases | solute carrier family 5 member 4 |
| Synonyms | DJ90G24.4, LOC100912626, LOC103690052, SAAT1, SGLT3, SGLT3-a, Slc5a4a, solute carrier family 5 member 4, solute carrier family 5, member 4a |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SLC5A4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- hydrogen ion transporter
- glucose:sodium symporter
- protein binding
- Solute carrier families 5 and 6-like; solute binding domain
- low-affinity glucose:sodium symporter
- transporter
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- cellular membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human SLC5A4 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- sodium ion transport
- sodium ion transmembrane transport
Cellular Component
Where in the cell the gene product is active
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- hydrogen ion transmembrane transporter activity
- glucose:sodium symporter activity