ZC3H7B Gene Summary [Human]

This gene encodes a protein that contains a tetratricopeptide repeat domain. The encoded protein also interacts with the rotavirus non-structural protein NSP3. [provided by RefSeq, Jul 2008]

Details

Type
Protein Coding
Official Symbol
ZC3H7B
Official Name
zinc finger CCCH-type containing 7B [Source:HGNC Symbol;Acc:HGNC:30869]
Ensembl ID
ENSG00000100403
Bio databases IDs NCBI: 23264 Ensembl: ENSG00000100403
Aliases zinc finger CCCH-type containing 7B
Synonyms Gm627, KIAA1031, mKIAA1031, RGD1307064, RoXaN, ROXAN1, Scrg3, Zc2h7b, ZC3H7B isoform 1, zinc finger CCCH-type containing 7B
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ZC3H7B often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Domain of Unknown Function (DUF3856)
  • Zinc-finger double-stranded RNA-binding
  • Tetratricopeptide repeats
  • Zinc finger C-x8-C-x5-C-x3-H type (and similar)
  • protein binding
  • tetratricopeptide repeat
  • RNA binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • pancreatic cancer
  • neuroticism
  • neurotic disorder
  • insomnia
  • breast carcinoma
  • infection by HIV-1
regulated by
  • Streptococcus pneumoniae TIGR4

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human ZC3H7B gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • posttranscriptional regulation of gene expression
  • production of miRNAs involved in gene silencing by miRNA

Cellular Component

Where in the cell the gene product is active
  • nucleus

Molecular Function

What the gene product does at the molecular level
  • miRNA binding
  • RNA binding
  • protein binding
  • metal ion binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.