RBM23 Gene Summary [Human]
This gene encodes a member of the U2AF-like family of RNA binding proteins. This protein interacts with some steroid nuclear receptors, localizes to the promoter of a steroid- responsive gene, and increases transcription of steroid-responsive transcriptional reporters in a hormone-dependent manner. It is also implicated in the steroid receptor-dependent regulation of alternative splicing. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Details
| Type | Protein Coding |
| Official Symbol | RBM23 |
| Official Name | RNA binding motif protein 23 [Source:HGNC Symbol;Acc:HGNC:20155] |
| Ensembl ID | ENSG00000100461 |
| Bio databases IDs | |
| Aliases | RNA binding motif protein 23, coactivator of activating protein-1 and estrogen receptors beta |
| Synonyms | CAPERbeta, PP239, RNA binding motif protein 23, RNPC4 |
| Species | Human, Homo sapiens |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human RBM23 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- RNA recognition motif (RRM) superfamily
- RNA recognition motif
- splicing factor, CC1-like family
- protein binding
- linker between RRM2 and RRM3 domains in RBM39 protein
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human RBM23 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- RNA splicing
- positive regulation of transcription, DNA-dependent
- regulation of nuclear mRNA splicing, via spliceosome
- mRNA processing
Cellular Component
Where in the cell the gene product is active
- nucleus
- membrane
Molecular Function
What the gene product does at the molecular level
- RNA binding
- protein binding