MTG2 Gene Summary [Human]
Small G proteins, such as GTPBP5, act as molecular switches that play crucial roles in the regulation of fundamental cellular processes such as protein synthesis, nuclear transport, membrane trafficking, and signal transduction (Hirano et al., 2006 [PubMed 17054726]).[supplied by OMIM, Mar 2008]
Details
| Type | Processed Transcript |
| Official Symbol | MTG2 |
| Official Name | mitochondrial ribosome associated GTPase 2 [Source:HGNC Symbol;Acc:HGNC:16239] |
| Ensembl ID | ENSG00000101181 |
| Bio databases IDs | |
| Aliases | mitochondrial ribosome associated GTPase 2 |
| Synonyms | 1810011P19Rik, 2900056P18RIK, D2Bwg0647e, dJ1005F21.2, GTPBP5, mitochondrial ribosome-associated GTPase 2, ObgH1 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human MTG2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- ADP-ribosylation factor family
- small GTP-binding protein domain
- 50S ribosome-binding GTPase
- GTPase
- enzyme
- Obg family GTPase CgtA
- P-loop containing Nucleoside Triphosphate Hydrolases
- GTP1/OBG
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
- mitochondrial matrix
- mitochondrial inner membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human MTG2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of respiratory system process
- ribosome biogenesis
- regulation of mitochondrial translation
Cellular Component
Where in the cell the gene product is active
- mitochondrial matrix
- mitochondrion
- mitochondrial ribosome
- mitochondrial inner membrane
Molecular Function
What the gene product does at the molecular level
- magnesium ion binding
- GTP binding
- GTPase activity