MT4 Gene Summary [Human]

Predicted to enable metal ion binding activity. Predicted to be involved in cellular response to metal ion; cellular zinc ion homeostasis; and detoxification of copper ion. Predicted to act upstream of or within cellular metal ion homeostasis. Predicted to be active in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
MT4
Official Name
metallothionein 4 [Source:HGNC Symbol;Acc:HGNC:18705]
Ensembl ID
ENSG00000102891
Bio databases IDs NCBI: 84560 Ensembl: ENSG00000102891
Aliases metallothionein 4
Synonyms metallothionein 4, MT-IV, RGD1565500
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human MT4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Metallothionein
  • metal ion binding

Pathways

Biological processes and signaling networks where the MT4 gene in human plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
disease
  • androgenic alopecia
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • cytosol

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human MT4 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • detoxification of copper ion
  • cellular response to zinc ion
  • cellular response to cadmium ion
  • cellular zinc ion homeostasis
  • cellular response to copper ion

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • cytoplasm

Molecular Function

What the gene product does at the molecular level
  • metal ion binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.