Mt4 Gene Summary [Mouse]

Enables metal ion binding activity. Acts upstream of or within intracellular monoatomic cation homeostasis. Predicted to be located in cytosol. Predicted to be active in cytoplasm and nucleus. Is expressed in decidua; decidua capsularis; embryo; liver; and tongue. Orthologous to human MT4 (metallothionein 4). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Mt4
Official Name
metallothionein 4 [Source:MGI Symbol;Acc:MGI:99692]
Ensembl ID
ENSMUSG00000031757
Bio databases IDs NCBI: 17752 Ensembl: ENSMUSG00000031757
Aliases metallothionein 4
Synonyms metallothionein 4, MT-IV, RGD1565500
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Mt4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Metallothionein
  • metal ion binding

Pathways

Biological processes and signaling networks where the Mt4 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
disease
  • androgenic alopecia
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • cytosol

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Mt4 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • detoxification of copper ion
  • cellular response to zinc ion
  • cellular response to cadmium ion
  • cellular zinc ion homeostasis
  • cellular response to copper ion

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • cytoplasm

Molecular Function

What the gene product does at the molecular level
  • metal ion binding