SNAPC2 Gene Summary [Human]
This gene encodes a subunit of the snRNA-activating protein complex which is associated with the TATA box-binding protein. The encoded protein is necessary for RNA polymerase II and III dependent small-nuclear RNA gene transcription. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2009]
Details
| Type | Protein Coding |
| Official Symbol | SNAPC2 |
| Official Name | small nuclear RNA activating complex polypeptide 2 [Source:HGNC Symbol;Acc:HGNC:11135] |
| Ensembl ID | ENSG00000104976 |
| Bio databases IDs | |
| Aliases | small nuclear RNA activating complex polypeptide 2 |
| Synonyms | 0610007H10RIK, PTFDELTA, small nuclear RNA activating complex polypeptide 2, small nuclear RNA activating complex, polypeptide 2, SNAP45 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SNAPC2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- transcription regulator
- Small nuclear RNA activating complex (SNAPc), subunit 2
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- non-insulin-dependent diabetes mellitus
- Alzheimer disease
regulated by
- 17-alpha-ethinylestradiol
- lipopolysaccharide
- SMARCA4
- tetrachlorodibenzodioxin
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nuclear fraction
- cytosol
- nucleoplasm
- nuclear bodies
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human SNAPC2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- transcription from RNA polymerase III promoter
- transcription from RNA polymerase II promoter
- snRNA transcription
Cellular Component
Where in the cell the gene product is active
- nucleus
- nuclear body
- cytosol
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- general RNA polymerase II transcription factor activity