SNAPC5 Gene Summary [Human]
This gene encodes a subunit of the small nuclear RNA (snRNA)-activating protein complex that plays a role in the transcription of snRNA genes. This complex binds to the promoters of snRNA genes transcribed by either RNA polymerase II or III and recruits other regulatory factors to activate snRNA gene transcription. The encoded protein may play a role in stabilizing this complex. A pseudogene of this gene has been identified on chromosome 6. [provided by RefSeq, Jul 2016]
Details
| Type | Protein Coding |
| Official Symbol | SNAPC5 |
| Official Name | small nuclear RNA activating complex polypeptide 5 [Source:HGNC Symbol;Acc:HGNC:15484] |
| Ensembl ID | ENSG00000174446 |
| Bio databases IDs | |
| Aliases | small nuclear RNA activating complex polypeptide 5 |
| Synonyms | 2010103A03RIK, LOC686858, small nuclear RNA activating complex polypeptide 5, small nuclear RNA activating complex, polypeptide 5, SNAP19 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SNAPC5 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- transcription regulator
- snRNA-activating protein complex subunit 19, SNAPc subunit 19
- protein binding
- general RNA polymerase II transcription factor
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm
- nucleoli
- nuclear bodies
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human SNAPC5 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- transcription initiation from RNA polymerase III promoter
- snRNA transcription from RNA polymerase II promoter
- snRNA transcription from RNA polymerase III promoter
Cellular Component
Where in the cell the gene product is active
- nucleus
- nuclear body
- nucleolus
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- general RNA polymerase II transcription factor activity
- core RNA polymerase III binding transcription factor activity