OLFM2 Gene Summary [Human]
Involved in positive regulation of smooth muscle cell differentiation. Acts upstream of or within protein secretion. Located in cytoplasm; extracellular region; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | OLFM2 |
| Official Name | olfactomedin 2 [Source:HGNC Symbol;Acc:HGNC:17189] |
| Ensembl ID | ENSG00000105088 |
| Bio databases IDs | |
| Aliases | olfactomedin 2, noelin 2 |
| Synonyms | A030009A06, A030009A06Rik, NOE2, NOELIN2, NOELIN2 V1, olfactomedin 2, OlfC |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human OLFM2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Olfactomedin-like domain
- Neurogenesis glycoprotein
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- glutaminergic synapse
- Extracellular Space
- Nucleus
- Plasma Membrane
- synaptic membrane
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human OLFM2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- signal transduction
- positive regulation of smooth muscle cell differentiation
- protein secretion
Cellular Component
Where in the cell the gene product is active
- alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex
- nucleus
- extracellular space
- cytoplasm
- synapse
- extracellular region
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding