LGALS13 Gene Summary [Human]
Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. The protein encoded by this gene has lysophospholipase activity. It is composed of two identical subunits which are held together by disulfide bonds. This protein has structural similarity to several members of the beta-galactoside-binding S-type lectin family. [provided by RefSeq, Jul 2008]
Details
| Type | Protein Coding |
| Official Symbol | LGALS13 |
| Official Name | galectin 13 [Source:HGNC Symbol;Acc:HGNC:15449] |
| Ensembl ID | ENSG00000105198 |
| Bio databases IDs | |
| Aliases | galectin 13 |
| Synonyms | GAL13, galectin 13, PLAC8, Placenta protein 13, PP13 |
| Species | Human, Homo sapiens |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human LGALS13 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- lysophospholipase
- enzyme
- protein binding
- GLECT
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Cytoplasm
- nucleoplasm
- nuclear bodies
- nuclear matrix
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human LGALS13 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- apoptotic process
- phospholipid metabolic process
Cellular Component
Where in the cell the gene product is active
- nuclear body
- cytoplasm
- nuclear matrix
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- lysophospholipase activity
- protein binding
- carbohydrate binding