DHX40 Gene Summary [Human]
This gene encodes a member of the DExH/D box family of ATP-dependent RNA helicases that have an essential role in RNA metabolism. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 17.[provided by RefSeq, Oct 2009]
Details
| Type | Protein Coding |
| Official Symbol | DHX40 |
| Official Name | DEAH-box helicase 40 [Source:HGNC Symbol;Acc:HGNC:18018] |
| Ensembl ID | ENSG00000108406 |
| Bio databases IDs | |
| Aliases | DEAH-box helicase 40 |
| Synonyms | 2410016C14Rik, ARG147, DDX40, DEAH-box helicase 40, PAD |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human DHX40 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Helicase associated domain (HA2)
- Helicase associated domain (HA2) Add an annotation
- Oligonucleotide/oligosaccharide-binding (OB)-fold
- DEAD/DEAH box helicase
- helicase superfamily c-terminal domain
- N-terminal helicase domain of the DEAD-box helicase superfamily
- enzyme
- protein binding
- DEAD-like helicases superfamily
- Helicase conserved C-terminal domain
- P-loop containing Nucleoside Triphosphate Hydrolases
- AAA domain
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human DHX40 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- intracellular
Molecular Function
What the gene product does at the molecular level
- ATPase activity
- ATP binding
- RNA binding
- protein binding
- RNA helicase activity
- helicase activity