Dhx40 Gene Summary [Mouse]
Predicted to enable 3'-5' RNA helicase activity and RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be part of spliceosomal complex. Is expressed in several structures, including adrenal gland; brain; gut; skeletal muscle tissue; and trigeminal nerve. Orthologous to human DHX40 (DEAH-box helicase 40). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Dhx40 |
| Official Name | DEAH (Asp-Glu-Ala-His) box polypeptide 40 [Source:MGI Symbol;Acc:MGI:1914737] |
| Ensembl ID | ENSMUSG00000018425 |
| Bio databases IDs | |
| Aliases | DEAH (Asp-Glu-Ala-His) box polypeptide 40 |
| Synonyms | 2410016C14Rik, ARG147, DDX40, DEAH-box helicase 40, PAD |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Dhx40 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Helicase associated domain (HA2)
- Helicase associated domain (HA2) Add an annotation
- Oligonucleotide/oligosaccharide-binding (OB)-fold
- DEAD/DEAH box helicase
- helicase superfamily c-terminal domain
- N-terminal helicase domain of the DEAD-box helicase superfamily
- enzyme
- protein binding
- DEAD-like helicases superfamily
- Helicase conserved C-terminal domain
- P-loop containing Nucleoside Triphosphate Hydrolases
- AAA domain
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Dhx40 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- intracellular
Molecular Function
What the gene product does at the molecular level
- ATPase activity
- ATP binding
- RNA binding
- protein binding
- RNA helicase activity
- helicase activity