TXNDC15 Gene Summary [Human]
This gene encodes a member of the thioredoxin superfamily. Members of this family are characterized by a conserved active motif called the thioredoxin fold that catalyzes disulfide bond formation and isomerization. [provided by RefSeq, Apr 2017]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | TXNDC15 |
| Official Name | thioredoxin domain containing 15 [Source:HGNC Symbol;Acc:HGNC:20652] |
| Ensembl ID | ENSG00000113621 |
| Bio databases IDs | |
| Aliases | thioredoxin domain containing 15 |
| Synonyms | 2310047H23Rik, BUG, C5orf14, LOC103690142, MKS14, RGD1304696, thioredoxin domain containing 15, UNQ335 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human TXNDC15 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold
- enzyme
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- cilia
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human TXNDC15 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cilium morphogenesis
- positive regulation of smoothened signaling pathway
Cellular Component
Where in the cell the gene product is active
- cilium
- cilium membrane
Molecular Function
What the gene product does at the molecular level
- protein binding