GPR89B Gene Summary [Human]
Enables voltage-gated anion channel activity. Involved in intracellular pH reduction. Located in Golgi cisterna membrane and Golgi-associated vesicle membrane. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | GPR89B |
| Official Name | G protein-coupled receptor 89B [Source:HGNC Symbol;Acc:HGNC:13840] |
| Ensembl ID | ENSG00000188092 |
| Bio databases IDs | |
| Aliases | G protein-coupled receptor 89B |
| Synonyms | GPHR, GPR89, GPR89C, G protein-coupled receptor 89B, LINC02804, LOC101060247, RP11 94I24, SH120, UNQ192 |
| Species | Human, Homo sapiens |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human GPR89B often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- Abscisic acid G-protein coupled receptor
- The Golgi pH Regulator (GPHR) Family N-terminal
Pathways
Biological processes and signaling networks where the GPR89B gene in human plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human GPR89B gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- T cell differentiation
- intracellular pH reduction
- protein transport
Cellular Component
Where in the cell the gene product is active
- Golgi cisterna membrane
- Golgi membrane
- ion channel complex
Molecular Function
What the gene product does at the molecular level
- voltage-gated anion channel activity
- protein binding