IQCG Gene Summary [Human]
Enables Hsp70 protein binding activity and calmodulin binding activity. Predicted to be involved in sperm axoneme assembly. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | IQCG |
| Official Name | IQ motif containing G [Source:HGNC Symbol;Acc:HGNC:25251] |
| Ensembl ID | ENSG00000114473 |
| Bio databases IDs | |
| Aliases | IQ motif containing G, dynein regulatory complex subunit 9 |
| Synonyms | 2400003L07RIK, AW215594, CFAP122, DRC9, esgd12d, G1-374-12, IQ motif containing G, repro1, stubby12d |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human IQCG often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Hsp70 protein binding
- Calmodulin-binding motif
- IQ (isoleucine-glutamine) motif containing G and D (IQCG and IQCD)
- calmodulin binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- motile cilia
- manchette
- actin cytoskeleton
- cytosol
- sperm tail
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human IQCG gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- spermatid development
- sperm axoneme assembly
Cellular Component
Where in the cell the gene product is active
- motile cilium
- extracellular vesicular exosome
- cytoplasm
- actin cytoskeleton
- cytosol
- sperm flagellum
- manchette
Molecular Function
What the gene product does at the molecular level
- calmodulin binding
- Hsp70 protein binding