Iqcg Gene Summary [Mouse]
Enables calmodulin binding activity. Involved in sperm axoneme assembly. Located in cytoplasm; manchette; and sperm flagellum. Is active in cytosol. Is expressed in brain; lung epithelium; and nose. Orthologous to human IQCG (IQ motif containing G). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Iqcg |
| Official Name | IQ motif containing G [Source:MGI Symbol;Acc:MGI:1916957] |
| Ensembl ID | ENSMUSG00000035578 |
| Bio databases IDs | |
| Aliases | IQ motif containing G |
| Synonyms | 2400003L07RIK, AW215594, CFAP122, DRC9, esgd12d, G1-374-12, IQ motif containing G, repro1, stubby12d |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Iqcg often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Hsp70 protein binding
- Calmodulin-binding motif
- IQ (isoleucine-glutamine) motif containing G and D (IQCG and IQCD)
- calmodulin binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- motile cilia
- manchette
- actin cytoskeleton
- cytosol
- sperm tail
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Iqcg gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- spermatid development
- sperm axoneme assembly
Cellular Component
Where in the cell the gene product is active
- motile cilium
- extracellular vesicular exosome
- cytoplasm
- actin cytoskeleton
- cytosol
- sperm flagellum
- manchette
Molecular Function
What the gene product does at the molecular level
- calmodulin binding
- Hsp70 protein binding