ACTL8 Gene Summary [Human]
Involved in epithelial cell differentiation. Predicted to be located in cytoplasm. Predicted to be part of dynactin complex. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | ACTL8 |
| Official Name | actin like 8 [Source:HGNC Symbol;Acc:HGNC:24018] |
| Ensembl ID | ENSG00000117148 |
| Bio databases IDs | |
| Aliases | actin like 8, cancer/testis antigen 57 |
| Synonyms | actin like 8, CT57, LOC81569 |
| Species | Human, Homo sapiens |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ACTL8 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Actin
- protein binding
- ASKHA_ATPase-like
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human ACTL8 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- epithelial cell differentiation
- skeletal muscle thin filament assembly
Cellular Component
Where in the cell the gene product is active
- striated muscle thin filament
- stress fiber
- actin cytoskeleton
- actin filament
Molecular Function
What the gene product does at the molecular level
- protein binding