HS1BP3 Gene Summary [Human]

The protein encoded by this gene shares similarity with mouse Hs1bp3, an Hcls1/Hs1-interacting protein that may be involved in lymphocyte activation. [provided by RefSeq, Jul 2008]

Details

Type
Protein Coding
Official Symbol
HS1BP3
Official Name
HCLS1 binding protein 3 [Source:HGNC Symbol;Acc:HGNC:24979]
Ensembl ID
ENSG00000118960
Bio databases IDs NCBI: 64342 Ensembl: ENSG00000118960
Aliases HCLS1 binding protein 3
Synonyms ETM2, FLJ14249, HCLS1 binding protein 3, RGD1311331
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human HS1BP3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • The Phox Homology domain, a phosphoinositide binding module
  • protein binding
  • PX domain

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • cardiovascular disorder
  • atrial fibrillation
  • androgenic alopecia
regulated by
role in cell
  • apoptosis
  • differentiation

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Endoplasmic Reticulum
  • Mitochondria

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human HS1BP3 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • regulation of apoptotic process

Cellular Component

Where in the cell the gene product is active
  • mitochondrion
  • endoplasmic reticulum

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • phosphatidylinositol binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.