Hs1bp3 Gene Summary [Rat]
Predicted to enable phosphatidylinositol binding activity. Predicted to be involved in regulation of apoptotic process. Predicted to be located in endoplasmic reticulum and mitochondrion. Orthologous to human HS1BP3 (HCLS1 binding protein 3). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Hs1bp3 |
| Official Name | HCLS1 binding protein 3 [Source:RGD Symbol;Acc:1311331] |
| Ensembl ID | ENSRNOG00000006062 |
| Bio databases IDs | |
| Aliases | HCLS1 binding protein 3 |
| Synonyms | ETM2, FLJ14249, HCLS1 binding protein 3, RGD1311331 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Hs1bp3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- The Phox Homology domain, a phosphoinositide binding module
- protein binding
- PX domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Endoplasmic Reticulum
- Mitochondria
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Hs1bp3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of apoptotic process
Cellular Component
Where in the cell the gene product is active
- mitochondrion
- endoplasmic reticulum
Molecular Function
What the gene product does at the molecular level
- protein binding
- phosphatidylinositol binding