HDHD3 Gene Summary [Human]

Located in nucleolus. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
HDHD3
Official Name
haloacid dehalogenase like hydrolase domain containing 3 [Source:HGNC Symbol;Acc:HGNC:28171]
Ensembl ID
ENSG00000119431
Bio databases IDs NCBI: 81932 Ensembl: ENSG00000119431
Aliases haloacid dehalogenase like hydrolase domain containing 3
Synonyms 2810435D12Rik, C9orf158, haloacid dehalogenase-like hydrolase domain containing 3, LOC682946
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human HDHD3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • HAD hydrolase, family IA, variant 1
  • histidinol-phosphate phosphatase family domain
  • HAD-superfamily hydrolase, subfamily IIIA
  • HAD-hyrolase-like
  • REG-2-like, HAD superfamily (subfamily IA) hydrolase
  • noncanonical pyrimidine nucleotidase, YjjG family
  • enzyme
  • protein binding
  • Haloacid Dehalogenase-like Hydrolases
  • HAD hydrolase, family IA, variant 3
  • haloacid dehalogenase-like hydrolase

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
  • MFSD2A
  • 2-amino-5-phosphonovaleric acid

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • intracellular membrane-bounded organelle
  • Mitochondria
  • nucleoli

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human HDHD3 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • intracellular membrane-bounded organelle
  • nucleolus

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.