DNAJC8 Gene Summary [Human]
Enables Hsp70 protein binding activity. Located in cytosol; intercellular bridge; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | DNAJC8 |
| Official Name | DnaJ heat shock protein family (Hsp40) member C8 [Source:HGNC Symbol;Acc:HGNC:15470] |
| Ensembl ID | ENSG00000126698 |
| Bio databases IDs | |
| Aliases | DnaJ heat shock protein family (Hsp40) member C8 |
| Synonyms | 1110021D09Rik, 2010009J04RIK, DnaJ heat shock protein family (Hsp40) member C8, HSPC331, SPF31 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human DNAJC8 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- DnaJ domain
- DnaJ
- Hsp70 protein binding
- DnaJ molecular chaperone homology domain
- protein binding
Pathways
Biological processes and signaling networks where the DNAJC8 gene in human plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- cytoplasmic bridges
- cytosol
- spliceosomes
- nucleoplasm
- nucleoli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human DNAJC8 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- nucleus
- intercellular bridge
- cytosol
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- Hsp70 protein binding