OMD Gene Summary [Human]
Predicted to be involved in cell adhesion and regulation of bone mineralization. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | OMD |
| Official Name | osteomodulin [Source:HGNC Symbol;Acc:HGNC:8134] |
| Ensembl ID | ENSG00000127083 |
| Bio databases IDs | |
| Aliases | osteomodulin, osteoadherin proteoglycan |
| Synonyms | KSPG osteomodulin, LOC100910891, LOC103690116, OSAD, Osteoadherin, osteomodulin, SLRR2C |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human OMD often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein phosphatase 1 regulatory subunit 42
- Leucine rich repeat
- Leucine rich repeat N-terminal domain
- Leucine Rich repeats (2 copies)
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- peripheral arterial disease
- urothelial bladder carcinoma
- transitional cell bladder cancer
- ulcerative colitis
- colorectal carcinomagenesis
- keratocystic odontogenic tumor
- keratocystic odontogenic tumors
- rectal adenocarcinoma
- rectum cancer
- head and neck squamous cell carcinoma
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- Golgi lumen
- lysosomal compartment
- extracellular matrix
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human OMD gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cell adhesion
Cellular Component
Where in the cell the gene product is active
- extracellular space
- extracellular vesicular exosome
- lysosomal lumen
- extracellular matrix
- Golgi lumen
- extracellular region