UQCR11 Gene Summary [Human]

This gene encodes the smallest known component of the ubiquinol-cytochrome c reductase complex, which forms part of the mitochondrial respiratory chain. The encoded protein may function as a binding factor for the iron-sulfur protein in this complex. [provided by RefSeq, Oct 2009]

Details

Type
Protein Coding
Official Symbol
UQCR11
Official Name
ubiquinol-cytochrome c reductase, complex III subunit XI [Source:HGNC Symbol;Acc:HGNC:30862]
Ensembl ID
ENSG00000127540
Bio databases IDs NCBI: 10975 Ensembl: ENSG00000127540
Aliases ubiquinol-cytochrome c reductase, complex III subunit XI, complex III subunit 10
Synonyms 0710008D09Rik, LOC686951, QCR10, Ubiquinol cytochrome c reductase 6.4kd, ubiquinol-cytochrome c reductase, complex III subunit XI, UQCR
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human UQCR11 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • electron carrier
  • enzyme
  • Ubiquinol-cytochrome-c reductase complex subunit (QCR10)

Pathways

Biological processes and signaling networks where the UQCR11 gene in human plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • Huntington disease
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • myelin enriched fraction
  • Mitochondria
  • mitochondrial inner membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human UQCR11 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • generation of precursor metabolites and energy
  • cellular respiration
  • mitochondrial electron transport, ubiquinol to cytochrome c

Cellular Component

Where in the cell the gene product is active
  • mitochondrial respiratory chain complex III
  • mitochondrial inner membrane

Molecular Function

What the gene product does at the molecular level
  • electron carrier activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.