TSPAN16 Gene Summary [Human]

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein might couple to signal transduction pathways and possibly modulate cellular activation and adhesion in haemopoietic and neural tissue. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]

Details

Type
Protein Coding
Official Symbol
TSPAN16
Official Name
tetraspanin 16 [Source:HGNC Symbol;Acc:HGNC:30725]
Ensembl ID
ENSG00000130167
Bio databases IDs NCBI: 26526 Ensembl: ENSG00000130167
Aliases tetraspanin 16
Synonyms tetraspanin 16, TM4-B, TM4SF16, TM-8
Species
Human, Homo sapiens

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human TSPAN16 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • tetraspanin_LEL
  • protein binding
  • Tetraspanin family

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • breast carcinoma
  • Alzheimer disease

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • cellular membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human TSPAN16 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • membrane
  • plasma membrane

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.