ENDOD1 Gene Summary [Human]
Predicted to enable endonuclease activity; metal ion binding activity; and nucleic acid binding activity. Predicted to be involved in nucleic acid phosphodiester bond hydrolysis. Located in extracellular exosome and membrane. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | ENDOD1 |
| Official Name | endonuclease domain containing 1 [Source:HGNC Symbol;Acc:HGNC:29129] |
| Ensembl ID | ENSG00000149218 |
| Bio databases IDs | |
| Aliases | endonuclease domain containing 1 |
| Synonyms | 2210414F18Rik, 2310067E08Rik, AABR07069219.1, endonuclease domain containing 1, ENSRNOG00000024757, KIAA0830, RGD1310444 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ENDOD1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- DNA/RNA non-specific endonuclease
- NUC
- enzyme
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human ENDOD1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- innate immune response
Cellular Component
Where in the cell the gene product is active
- extracellular vesicular exosome
- membrane
- cytosol
- extracellular region
Molecular Function
What the gene product does at the molecular level
- nucleic acid binding
- protein binding
- metal ion binding
- endonuclease activity