DCAF15 Gene Summary [Human]
Enables small molecule binding activity. Involved in protein polyubiquitination and regulation of natural killer cell activation. Part of Cul4-RING E3 ubiquitin ligase complex. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | DCAF15 |
| Official Name | DDB1 and CUL4 associated factor 15 [Source:HGNC Symbol;Acc:HGNC:25095] |
| Ensembl ID | ENSG00000132017 |
| Bio databases IDs | |
| Aliases | DDB1 and CUL4 associated factor 15 |
| Synonyms | 6720484B16, C19orf72, DDB1 and CUL4 associated factor 15, RGD1304881 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human DCAF15 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- N-terminal domain of DDB1- and CUL4-associated factor 15
- binding protein
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human DCAF15 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of natural killer cell activation
- protein polyubiquitination
- immune system process
- protein ubiquitination
Cellular Component
Where in the cell the gene product is active
- CUL4 RING ubiquitin ligase complex
Molecular Function
What the gene product does at the molecular level
- protein binding
- metal ion binding
- small molecule binding