RNF121 Gene Summary [Human]

The protein encoded by this gene contains a RING finger, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. Several alternatively spliced transcript variants have been noted for this gene, however, not all are likely to encode viable protein products. [provided by RefSeq, Sep 2008]

Details

Type
Nonsense Mediated Decay
Official Symbol
RNF121
Official Name
ring finger protein 121 [Source:HGNC Symbol;Acc:HGNC:21070]
Ensembl ID
ENSG00000137522
Bio databases IDs NCBI: 55298 Ensembl: ENSG00000137522
Aliases ring finger protein 121
Synonyms 4930544L10RIK, ring finger protein 121
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human RNF121 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • RING finger (Really Interesting New Gene) domain and U-box domain superfamily
  • Ring finger
  • Ring finger domain
  • Zinc finger, C3HC4 type (RING finger)

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • non-insulin-dependent diabetes mellitus
regulated by
regulates
role in cell
  • molecular cleavage in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human RNF121 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • protein ubiquitination

Cellular Component

Where in the cell the gene product is active
  • endoplasmic reticulum membrane
  • Golgi membrane

Molecular Function

What the gene product does at the molecular level
  • metal ion binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.