CALHM2 Gene Summary [Human]
Predicted to enable cation channel activity. Involved in positive regulation of apoptotic process. Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | CALHM2 |
| Official Name | calcium homeostasis modulator family member 2 [Source:HGNC Symbol;Acc:HGNC:23493] |
| Ensembl ID | ENSG00000138172 |
| Bio databases IDs | |
| Aliases | calcium homeostasis modulator family member 2 |
| Synonyms | 2810048G17Rik, calcium homeostasis modulator family member 2, FAM26B, RGD1308276 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human CALHM2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Calcium homeostasis modulator
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cellular membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human CALHM2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- calcium ion import
- positive regulation of apoptotic process
- regulation of synaptic plasticity
Cellular Component
Where in the cell the gene product is active
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- cation channel activity