Calhm2 Gene Summary [Rat]
Predicted to enable monoatomic cation channel activity. Predicted to be involved in several processes, including ATP export; calcium ion import; and regulation of microglial cell activation. Predicted to be active in plasma membrane. Orthologous to human CALHM2 (calcium homeostasis modulator family member 2). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Calhm2 |
| Official Name | calcium homeostasis modulator family member 2 [Source:RGD Symbol;Acc:1308276] |
| Ensembl ID | ENSRNOG00000020325 |
| Bio databases IDs | |
| Aliases | calcium homeostasis modulator family member 2 |
| Synonyms | 2810048G17Rik, calcium homeostasis modulator family member 2, FAM26B, RGD1308276 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Calhm2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Calcium homeostasis modulator
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cellular membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Calhm2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- calcium ion import
- positive regulation of apoptotic process
- regulation of synaptic plasticity
Cellular Component
Where in the cell the gene product is active
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- cation channel activity