Calhm2

Predicted to enable monoatomic cation channel activity. Involved in several processes, including ATP export; calcium ion import; and regulation of microglial cell activation. Located in plasma membrane. Is expressed in several structures, including brain; genitourinary system; gut; hemolymphoid system gland; and skin. Orthologous to human CALHM2 (calcium homeostasis modulator family member 2). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Calhm2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the mouse Calhm2 gene, providing context for its role in the cell.