GUCA1C Gene Summary [Human]

Predicted to enable calcium ion binding activity and calcium sensitive guanylate cyclase activator activity. Predicted to be involved in signal transduction. Predicted to be located in photoreceptor disc membrane. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
GUCA1C
Official Name
guanylate cyclase activator 1C [Source:HGNC Symbol;Acc:HGNC:4680]
Ensembl ID
ENSG00000138472
Bio databases IDs NCBI: 9626 Ensembl: ENSG00000138472
Aliases guanylate cyclase activator 1C, guanylyl cyclase-activating protein 3
Synonyms GCAP3, guanylate cyclase activator 1C
Species
Human, Homo sapiens

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human GUCA1C often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • EF-hand, calcium binding motif
  • EF-hand domain
  • calcium sensitive guanylate cyclase activator
  • EF-hand domain pair
  • EF hand
  • EFh
  • Eps15 homology domain
  • protein binding
  • EFh_PI-PLC

Pathways

Biological processes and signaling networks where the GUCA1C gene in human plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • pelvic organ prolapse
regulated by
regulates
role in cell
  • activation in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • cellular membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human GUCA1C gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • signal transduction
  • visual perception

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • calcium ion binding
  • calcium sensitive guanylate cyclase activator activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.