BAHD1 Gene Summary [Human]
Enables chromatin binding activity. Involved in heterochromatin assembly and negative regulation of transcription, DNA-templated. Located in nucleoplasm. Part of chromatin silencing complex. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | BAHD1 |
| Official Name | bromo adjacent homology domain containing 1 [Source:HGNC Symbol;Acc:HGNC:29153] |
| Ensembl ID | ENSG00000140320 |
| Bio databases IDs | |
| Aliases | bromo adjacent homology domain containing 1 |
| Synonyms | AW541238, bromo adjacent homology domain containing 1, Gm117, mKIAA0945, RGD1563127 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human BAHD1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- BAH
- BAH domain
- chromatin binding
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- infection by HIV-1
- non-insulin-dependent diabetes mellitus
- infection by bacteria
regulated by
- histone H3
- KLF3
- levodopa
role in cell
- expression in
- formation in
- formation
- repression in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- heterochromatin
- nuclear foci
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human BAHD1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of transcription, DNA-dependent
- heterochromatin assembly
Cellular Component
Where in the cell the gene product is active
- chromosome
- chromatin silencing complex
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- transcription regulatory region sequence-specific DNA binding
- chromatin binding