DISP2 Gene Summary [Human]
This gene is one of two human homologs of a segment-polarity gene known as dispatched identified in Drosophila. The product of this gene may be required for normal Hedgehog (Hh) signaling during embryonic pattern formation. [provided by RefSeq, Jan 2017]
Details
| Type | Protein Coding |
| Official Symbol | DISP2 |
| Official Name | dispatched RND transporter family member 2 [Source:HGNC Symbol;Acc:HGNC:19712] |
| Ensembl ID | ENSG00000140323 |
| Bio databases IDs | |
| Aliases | dispatched RND transporter family member 2 |
| Synonyms | B230210L08Rik, C15orf36, dispatched RND transporter family member 2, DISPB, HsT16908, LINC00594, mKIAA1742 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human DISP2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- BAX inhibitor (BI)-1/YccA-like protein family
- Sterol-sensing domain of SREBP cleavage-activation
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human DISP2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- transmembrane transport
- smoothened signaling pathway
Cellular Component
Where in the cell the gene product is active
- membrane
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- transmembrane transporter activity