DPEP3 Gene Summary [Human]

This gene encodes a membrane-bound glycoprotein from the family of dipeptidases involved in hydrolytic metabolism of various dipeptides, including penem and carbapenem beta-lactam antibiotics. This gene is located on chromosome 16 in a cluster with another member of this family. Alternatively spliced transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Details

Type
Protein Coding
Official Symbol
DPEP3
Official Name
dipeptidase 3 [Source:HGNC Symbol;Acc:HGNC:23029]
Ensembl ID
ENSG00000141096
Bio databases IDs NCBI: 64180 Ensembl: ENSG00000141096
Aliases dipeptidase 3
Synonyms 1700018F16Rik, dipeptidase 3, MBD-3, MLZ-136
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human DPEP3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • dipeptidase
  • peptidase
  • protein binding
  • metallo-dependent_hydrolases

Pathways

Biological processes and signaling networks where the DPEP3 gene in human plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • refractive error
regulated by
regulates
  • bis(-S-cysteinylglycine)

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • cellular membrane
  • Plasma Membrane
  • acrosome

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human DPEP3 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • proteolysis

Cellular Component

Where in the cell the gene product is active
  • acrosomal vesicle
  • membrane
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • dipeptidase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.