RABL3 Gene Summary [Human]
Predicted to enable GTP binding activity; GTPase activity; and protein homodimerization activity. Involved in regulation of Ras protein signal transduction and regulation of protein lipidation. Predicted to be active in endomembrane system. Implicated in pancreatic cancer. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | RABL3 |
| Official Name | RAB, member of RAS oncogene family like 3 [Source:HGNC Symbol;Acc:HGNC:18072] |
| Ensembl ID | ENSG00000144840 |
| Bio databases IDs | |
| Aliases | RAB, member of RAS oncogene family like 3 |
| Synonyms | 4930553C05Rik, MGC23920, PNCA5, RAB, member of RAS oncogene family-like 3, RAB, member RAS oncogene family-like 3 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human RABL3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- GTP binding
- small GTP-binding protein domain
- Ras family
- protein homodimerization
- protein binding
- Ras of Complex, Roc, domain of DAPkinase
- P-loop containing Nucleoside Triphosphate Hydrolases
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human RABL3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- B cell differentiation
- T cell differentiation in thymus
- natural killer cell differentiation
- regulation of Ras protein signal transduction
- intracellular protein transport
- protein stabilization
Cellular Component
Where in the cell the gene product is active
- endomembrane system
Molecular Function
What the gene product does at the molecular level
- GTP binding
- protein homodimerization activity
- protein binding
- GTPase activity