Rabl3 Gene Summary [Mouse]
Enables GTP binding activity and protein homodimerization activity. Involved in lymphocyte differentiation and protein stabilization. Predicted to be active in endomembrane system. Is expressed in acoustic ganglion; otocyst; and urinary system. Human ortholog(s) of this gene implicated in pancreatic cancer. Orthologous to human RABL3 (RAB, member of RAS oncogene family like 3). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rabl3 |
| Official Name | RAB, member RAS oncogene family-like 3 [Source:MGI Symbol;Acc:MGI:1914907] |
| Ensembl ID | ENSMUSG00000022827 |
| Bio databases IDs | |
| Aliases | RAB, member RAS oncogene family-like 3 |
| Synonyms | 4930553C05Rik, MGC23920, PNCA5, RAB, member of RAS oncogene family-like 3, RAB, member RAS oncogene family-like 3 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rabl3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- GTP binding
- small GTP-binding protein domain
- Ras family
- protein homodimerization
- protein binding
- Ras of Complex, Roc, domain of DAPkinase
- P-loop containing Nucleoside Triphosphate Hydrolases
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Rabl3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- B cell differentiation
- T cell differentiation in thymus
- natural killer cell differentiation
- regulation of Ras protein signal transduction
- intracellular protein transport
- protein stabilization
Cellular Component
Where in the cell the gene product is active
- endomembrane system
Molecular Function
What the gene product does at the molecular level
- GTP binding
- protein homodimerization activity
- protein binding
- GTPase activity