NICN1 Gene Summary [Human]

This protein encoded by this gene localizes to the nucleus and is expressed in numerous tissues including brain, testis, liver, and kidney. This refseq contains genomic sequence in its 3' UTR which is not supported by experimental evidence. Computer predictions indicate that this region of the 3' UTR contains hairpin-forming self-complementary sequence which is possibly excised after transcription. This gene has a pseudogene on chromosome X. [provided by RefSeq, Jul 2008]

Details

Type
Protein Coding
Official Symbol
NICN1
Official Name
nicolin 1 [Source:HGNC Symbol;Acc:HGNC:18317]
Ensembl ID
ENSG00000145029
Bio databases IDs NCBI: 84276 Ensembl: ENSG00000145029
Aliases nicolin 1, nicolin 1, tubulin polyglutamylase complex subunit
Synonyms 1500032A17Rik, nicolin 1, nicolin 1, tubulin polyglutamylase complex subunit, p24, PGs5
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human NICN1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • non-ketotic hyperglycinemia
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • cytosol
  • nucleoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human NICN1 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • nucleoplasm
  • microtubule

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.