SERP2 Gene Summary [Human]
Predicted to be involved in endoplasmic reticulum unfolded protein response and protein glycosylation. Predicted to be located in endoplasmic reticulum membrane. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | SERP2 |
| Official Name | stress associated endoplasmic reticulum protein family member 2 [Source:HGNC Symbol;Acc:HGNC:20607] |
| Ensembl ID | ENSG00000151778 |
| Bio databases IDs | |
| Aliases | stress associated endoplasmic reticulum protein family member 2 |
| Synonyms | 2810032E02Rik, bA269C23.1, C13orf21, LOC107984603, RGD1566076, stress-associated endoplasmic reticulum protein family member 2 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SERP2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Ribosome associated membrane protein RAMP4
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- epithelial cancer
- prostate cancer
- endometrial adenocarcinoma
- endometrial adenocarcinoma formation
- lung squamous cell carcinoma
- squamous cell lung cancer
- lung adenocarcinoma
- lung adenocarcinoma formation
- prostatic adenocarcinoma
- urothelial bladder carcinoma
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human SERP2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- endoplasmic reticulum unfolded protein response
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- endoplasmic reticulum
Molecular Function
What the gene product does at the molecular level
- protein binding