SLC10A6 Gene Summary [Human]

Predicted to enable bile acid:sodium symporter activity. Predicted to be involved in bile acid and bile salt transport. Predicted to be located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
SLC10A6
Official Name
solute carrier family 10 member 6 [Source:HGNC Symbol;Acc:HGNC:30603]
Ensembl ID
ENSG00000145283
Bio databases IDs NCBI: 345274 Ensembl: ENSG00000145283
Aliases solute carrier family 10 member 6
Synonyms 8430417G17Rik, SOAT, solute carrier family 10 member 6, solute carrier family 10 (sodium/bile acid cotransporter family), member 6
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SLC10A6 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • bile acid:sodium symporter
  • bile acid transporter
  • protein binding
  • Sodium Bile acid symporter family
  • organic anion transporter
  • Predicted Na+-dependent transporter YfeH [General function prediction only]
  • transporter

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
regulates
  • dehydroepiandrosterone sulfate
  • estrone sulfate
  • 4-sulfooxymethylpyrene
  • 2-sulfooxymethylpyrene
  • taurolithocholate-3-sulfate
  • pregnenolone sulfate

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human SLC10A6 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • sodium ion transport
  • transmembrane transport
  • sodium-dependent organic anion transport
  • bile acid and bile salt transport

Cellular Component

Where in the cell the gene product is active
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • bile acid:sodium symporter activity
  • protein binding
  • sodium-dependent organic anion transmembrane transporter activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.