MZT2B Gene Summary [Human]

Located in cytosol; microtubule cytoskeleton; and nucleoplasm. Part of gamma-tubulin large complex. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
MZT2B
Official Name
mitotic spindle organizing protein 2B [Source:HGNC Symbol;Acc:HGNC:25886]
Ensembl ID
ENSG00000152082
Bio databases IDs NCBI: 80097 Ensembl: ENSG00000152082
Aliases mitotic spindle organizing protein 2B, mitotic-spindle organizing protein associated with a ring of gamma-tubulin 2B
Synonyms FAM128B, FLJ14346, mitotic spindle organizing protein 2B, MOZART2B
Species
Human, Homo sapiens

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human MZT2B often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Mitotic-spindle organizing gamma-tubulin ring associated
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • Alzheimer disease
  • rotator cuff injury

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • spindle apparatus
  • centrosome
  • cytosol
  • nucleoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human MZT2B gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • centrosome
  • spindle
  • cytosol
  • gamma-tubulin large complex
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.