LGI2 Gene Summary [Human]
Predicted to be involved in inhibitory synapse assembly. Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | LGI2 |
| Official Name | leucine rich repeat LGI family member 2 [Source:HGNC Symbol;Acc:HGNC:18710] |
| Ensembl ID | ENSG00000153012 |
| Bio databases IDs | |
| Aliases | leucine rich repeat LGI family member 2 |
| Synonyms | leucine rich repeat LGI family member 2, leucine-rich repeat LGI family, member 2, LGIL2, mKIAA1916 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human LGI2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Leucine-rich repeats, outliers
- Leucine-rich repeats, typical (most populated) subfamily
- Leucine rich repeat
- Leucine rich repeat C-terminal domain
- protein binding
- EPTP domain
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- cell surface
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human LGI2 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- extracellular region