Lgi2 Gene Summary [Mouse]
Involved in inhibitory synapse assembly. Located in extracellular space. Is expressed in several structures, including alimentary system; brain; nose; orbito-sphenoid; and salivary gland primordium. Orthologous to human LGI2 (leucine rich repeat LGI family member 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Lgi2 |
| Official Name | leucine-rich repeat LGI family, member 2 [Source:MGI Symbol;Acc:MGI:2180196] |
| Ensembl ID | ENSMUSG00000039252 |
| Bio databases IDs | |
| Aliases | leucine-rich repeat LGI family, member 2 |
| Synonyms | leucine rich repeat LGI family member 2, leucine-rich repeat LGI family, member 2, LGIL2, mKIAA1916 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Lgi2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Leucine-rich repeats, outliers
- Leucine-rich repeats, typical (most populated) subfamily
- Leucine rich repeat
- Leucine rich repeat C-terminal domain
- protein binding
- EPTP domain
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- cell surface
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Lgi2 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- extracellular region