Lgi2 Gene Summary [Rat]

Predicted to be involved in inhibitory synapse assembly. Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
Lgi2
Official Name
leucine-rich repeat LGI family, member 2 [Source:RGD Symbol;Acc:1310391]
Ensembl ID
ENSRNOG00000003887
Bio databases IDs NCBI: 305417 Ensembl: ENSRNOG00000003887
Aliases leucine-rich repeat LGI family, member 2
Synonyms leucine rich repeat LGI family member 2, leucine-rich repeat LGI family, member 2, LGIL2, mKIAA1916
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Lgi2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Leucine-rich repeats, outliers
  • Leucine-rich repeats, typical (most populated) subfamily
  • Leucine rich repeat
  • Leucine rich repeat C-terminal domain
  • protein binding
  • EPTP domain

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • tremor
  • growth failure
regulated by
role in cell
  • assembly
  • abnormal morphology

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Extracellular Space
  • cell surface

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Lgi2 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • extracellular region

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.