SLFN13 Gene Summary [Human]
Enables endoribonuclease activity. Involved in rRNA catabolic process and tRNA catabolic process. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | SLFN13 |
| Official Name | schlafen family member 13 [Source:HGNC Symbol;Acc:HGNC:26481] |
| Ensembl ID | ENSG00000154760 |
| Bio databases IDs | |
| Aliases | schlafen family member 13 |
| Synonyms | hSLFN13, rSLFN13, schlafen family member 13, schlafen family member 9, SLFN10, Slfn8, Slfn9 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SLFN13 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- tRNA binding
- Putative DNA-binding domain
- zinc ion binding
- endoribonuclease
- enzyme
- ATPase
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Nucleus
- cytosol
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human SLFN13 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- rRNA catabolic process
- defense response to virus
- tRNA catabolic process
Cellular Component
Where in the cell the gene product is active
- cytoplasm
Molecular Function
What the gene product does at the molecular level
- ATP binding
- zinc ion binding
- tRNA binding
- endoribonuclease activity