Slfn13 Gene Summary [Rat]
Enables RNA endonuclease activity and zinc ion binding activity. Involved in rRNA catabolic process and tRNA decay. Predicted to be located in cytosol; nucleoplasm; and site of DNA damage. Orthologous to human SLFN11 (schlafen family member 11) and SLFN13 (schlafen family member 13). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Slfn13 |
| Official Name | schlafen family member 13 [Source:RGD Symbol;Acc:1359139] |
| Ensembl ID | ENSRNOG00000021412 |
| Bio databases IDs | |
| Aliases | schlafen family member 13 |
| Synonyms | hSLFN13, rSLFN13, schlafen family member 13, schlafen family member 9, SLFN10, Slfn8, Slfn9 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Slfn13 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- tRNA binding
- Putative DNA-binding domain
- zinc ion binding
- endoribonuclease
- enzyme
- ATPase
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Nucleus
- cytosol
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Slfn13 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- rRNA catabolic process
- defense response to virus
- tRNA catabolic process
Cellular Component
Where in the cell the gene product is active
- cytoplasm
Molecular Function
What the gene product does at the molecular level
- ATP binding
- zinc ion binding
- tRNA binding
- endoribonuclease activity