ANKRD9 Gene Summary [Human]
Enables ubiquitin ligase-substrate adaptor activity. Involved in cellular copper ion homeostasis; proteasome-mediated ubiquitin-dependent protein catabolic process; and protein ubiquitination. Located in cytoplasmic vesicle and cytosol. Part of Cul5-RING ubiquitin ligase complex. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | ANKRD9 |
| Official Name | ankyrin repeat domain 9 [Source:HGNC Symbol;Acc:HGNC:20096] |
| Ensembl ID | ENSG00000156381 |
| Bio databases IDs | |
| Aliases | ankyrin repeat domain 9 |
| Synonyms | 2500003O20Rik, ankyrin repeat domain 9 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ANKRD9 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding activity, bridging
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
- cytoplasmic vesicles
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human ANKRD9 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- proteasomal ubiquitin-dependent protein catabolic process
- cellular copper ion homeostasis
- protein ubiquitination
Cellular Component
Where in the cell the gene product is active
- cytosol
- cytoplasmic vesicle
- Cul5-RING ubiquitin ligase complex